Best In-Office Treatments to Boost Your Collagen Production | Cosmetic Laser Dermatology. Looking to restore youthful, firm skin? Explore dermatologist-approved in-office treatments like Accure, Fraxel, and RF Microneedling to boost collagen and improve skin texture. Book your consultation today!

How to Restore Collagen for Youthful, Radiant Skin

Collagen is the foundation of firm, youthful skin. As we age, our natural production of collagen, elastin, and hyaluronic acid declines, leading to fine lines, wrinkles, and loss of elasticity. Fortunately, advanced dermatological treatments can stimulate collagen regeneration, improve skin texture, and restore a youthful glow.


Top Dermatologist-Recommended Collagen Treatments

Below, our board-certified dermatologists at Cosmetic Laser Dermatology outline the best in-office collagen-boosting treatments for firmer, healthier skin.

1. Accure Laser – Best for Acne-Prone Skin

The Accure Laser is an advanced treatment originally designed for acne. It targets sebaceous glands while heating deep layers of skin to boost collagen production, refine pores, and improve texture.

Results: Clearer skin, refined texture over several weeks
Downtime: Minimal (mild redness or swelling)
Best for: Acne-prone individuals seeking smoother, firmer skin

Learn more about Accure Laser for acne and skin rejuvenation.

Before and after results of Accure Laser treatment for acne, showing smoother skin, reduced breakouts, and improved skin texture,
Before and after results of Accure Laser treatment for acne, showing smoother skin, reduced breakouts, and improved skin texture,

2. ActiveFX & DeepFX – Best for Wrinkle Reduction

Patient undergoing ActiveFX & DeepFX fractional CO2 laser treatment to reduce wrinkles, fine lines, and improve skin firmness.
Patient undergoing ActiveFX & DeepFX fractional CO2 laser treatment to reduce wrinkles, fine lines, and improve skin firmness.

These fractional CO2 laser treatments create controlled micro-injuries in the skin, stimulating deep collagen remodeling and skin renewal.

Results: Smoother, firmer skin with fewer fine lines and wrinkles
Downtime: Moderate (redness, peeling for a few days)
Best for: Patients seeking advanced anti-aging treatments

Explore our CO2 laser skin resurfacing options.


3. Affirm Multiplex – Best for Pigmentation & Texture

Using dual wavelengths, the Affirm Multiplex laser targets different skin layers to stimulate collagen, elastin, and hyaluronic acid growth, while reducing pigmentation and improving texture.

Results: Gradual improvement in skin smoothness and firmness
Downtime: Minimal (mild redness and swelling)
Best for: Those looking for mild to moderate skin rejuvenation

Discover how Affirm Multiplex improves pigmentation and skin tone.

Before and after oblique image of Affirm laser treatment on a female's facial wrinkles performed by Dr. Groff at our San Diego medical clinic
Actual un-retouched patient before and after Affirm laser treatment for wrinkle reduction. Disclaimer: Results may vary from patient to patient. Results are not guaranteed.

4. Clear & Brilliant – Best for Preventative Anti-Aging

Before and after comparison of Clear & Brilliant laser treatment, highlighting enhanced skin tone, brightness, and elasticity.
Before and after comparison of Clear & Brilliant laser treatment, highlighting enhanced skin tone, brightness, and elasticity.

The Clear & Brilliant laser is a gentle fractional laser that creates thousands of microscopic treatment zones, stimulating collagen production while improving skin tone and elasticity.

Results: Brighter, firmer skin with minimal downtime
Downtime: 1-2 days (redness, mild sensitivity)
Best for: Those looking for a preventative anti-aging solution

Find out why Clear & Brilliant is the go-to laser for youthful skin.


5. Fraxel Dual / Repair / Restore – Best for Sun Damage & Scarring

The Fraxel Laser uses microscopic laser columns to penetrate deep into the skin, improving wrinkles, sun damage, and acne scars while stimulating long-term collagen growth.

Results: Reduction in wrinkles, hyperpigmentation, and scarring
Downtime: Varies (minimal for Dual/Restore, moderate for Repair)
Best for: Those looking for customizable laser treatments

Discover how Fraxel laser therapy can transform your skin.

Hand rejuvenation before and after Fraxel Dual laser treatment, reducing age spots, fine lines, and improving skin texture.
Hand rejuvenation before and after Fraxel Dual laser treatment, reducing age spots, fine lines, and improving skin texture.

6. Potenza RF Microneedling – Best for Skin Tightening

Close-up of a patient receiving Potenza RF Microneedling, a collagen-boosting treatment for firmer skin and improved texture.
Close-up of a patient receiving Potenza RF Microneedling, a collagen-boosting treatment for firmer skin and improved texture.

Potenza combines microneedling with radiofrequency energy, delivering controlled heat into deeper skin layers to boost collagen, tighten skin, and refine texture.

Results: Gradual improvement in firmness, elasticity, and texture
Downtime: Mild (redness, slight swelling for a few days)
Best for: Patients looking for non-surgical skin tightening

Learn how RF Microneedling stimulates collagen and lifts sagging skin.


7. ResurFX – Best for Skin Renewal

ResurFX is a non-ablative fractional laser that enhances collagen remodeling while improving skin texture and elasticity with minimal discomfort and downtime.

Results: Gradual skin tightening and texture refinement
Downtime: Minimal (some redness and mild swelling)
Best for: Patients seeking gentle yet effective skin renewal

Explore how ResurFX renews and revitalizes skin.

ResurFX to treat scar on nose by Dr. Goldman. After treatment, the patient's scar has almost disappeared.
Before and after photos of ResurFX laser treatment by Dr. Goldman, showing gradual skin tightening and refined texture with minimal downtime.

8. Sciton Profile – Best for Custom Laser Resurfacing

Before and after oblique image of Sciton Profile erbium and fractional laser resurfacing treatment on a male's area under the eyes performed by Dr. Goldman at our San Diego medical spa.
Before and after oblique image of Sciton Profile erbium and fractional laser resurfacing treatment on a male’s area under the eyes performed by Dr. Goldman at our San Diego medical spa.

This advanced laser system offers erbium and fractional laser treatments to resurface skin, improve tone, and encourage collagen remodeling.

Results: Smoother, firmer skin with reduced imperfections
Downtime: Varies depending on the specific laser treatment
Best for: Individuals looking for customizable laser treatments

Learn more about Sciton Profile laser resurfacing.


9. UltraClear – Best for Non-Invasive Collagen Boost

UltraClear is a fractional laser treatment designed to promote collagen, hyaluronic acid, and elastin fiber regeneration.

Results: Brighter, firmer, and healthier skin
Downtime: Minimal (some redness and sensitivity)
Best for: Patients looking for a non-invasive collagen boost

Discover how UltraClear laser enhances skin quality.

Close-up of UltraClear laser treatment in action, stimulating collagen, reducing fine lines, and enhancing skin brightness.
Close-up of UltraClear laser treatment in action, stimulating collagen, reducing fine lines, and enhancing skin brightness.

10. UltraPulse CO2 Laser – Best for Deep Wrinkle Reduction

Before and after UltraPulse CO2 laser resurfacing, showing dramatic reduction in deep wrinkles and improved skin texture.
Before and after UltraPulse CO2 laser resurfacing, showing dramatic reduction in deep wrinkles and improved skin texture.

The UltraPulse CO2 laser penetrates deep into the skin to resurface damaged tissue and stimulate long-term collagen production.

Results: Significant reduction in wrinkles, scars, and texture irregularities
Downtime: Moderate to significant, depending on intensity
Best for: Individuals seeking dramatic skin rejuvenation

Learn more about UltraPulse CO2 laser for deep wrinkle reduction.


How Collagen-Stimulating Treatments Work

Scientific research has shown that laser therapy, microneedling, and radiofrequency treatments effectively stimulate collagen production, improve skin elasticity, and reduce signs of aging. Studies indicate that fractional lasers and RF microneedling trigger neocollagenesis—the process of new collagen formation—leading to long-term skin rejuvenation and improved texture.

For more scientific insights on collagen stimulation and dermatology treatments, explore the National Center for Biotechnology Information (NCBI) database.


Which Collagen Treatment Is Right for You?

With so many innovative options available, choosing the right treatment depends on your skin type, goals, and downtime preference. At Cosmetic Laser Dermatology, our 7 board-certified dermatologists specialize in customized, results-driven skin treatments.

Want expert guidance? Book a consultation today and get a personalized skincare plan!

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