Cosmetic Laser Dermatology works hard to remain at the forefront of laser and cosmetic surgery research while maintaining the highest industry standards. Our studies are conducted by board-certified dermatologists in pursuit of advancing the field of cosmetic and laser dermatology while optimizing the appearance of your skin in the process. We’ve been a part of over 280 studies since 1974!

Eligible trial participants may receive free treatment and even additional compensation for their particular trial provided they participate fully in all necessary observation periods, reporting sessions with the doctors, etc. for the duration of the study.

Please call 858-657-1004 or email [email protected] to see if you are eligible for one of our studies.

Learn what it's like to be enrolled in our studies

Participating in a clinical trial is not unlike going to a doctor’s appointment. You will meet with the coordinator and investigator for the trial to determine whether you are eligible to participate in the trial, which may require lab work or additional evaluations. Once enrolled, participants attend a treatment visit to receive the medication or treatment, which may take 30 minutes to two hours depending on the medication, injectable product, laser or device that is being tested. In order to monitor the results, participants may be asked to return for a follow-up appointment weekly, monthly, or every three months, depending on the treatment.

In many cases, clinical trial sponsors often provide participants with compensation for their time. To participate in additional studies, participants must wait at least 30 days after concluding a trial before they can be considered eligible.

If you are interested in participating in one of our many exciting clinical research studies, please provide us with as much information as possible and a member of our research team will contact you shortly.


Healthy Males/Females 22-75yrs

Concern :
Midface volume deficiency

Study Specifics:
To evaluate the safety and effectiveness of dermal filler
called saypha VOLUME Lidocaine when compared to Voluma in the treatment of midface volume deficiency

Up to 92 weeks (12-19 visits)

Up to $1250

Arm laxity

Females 40-70yrs

Concern :
Moderate to severe upper inner arm crepiness/laxity

Study Specifics:

This trial will assess the safety, efficacy, and subject satisfaction associated with the treatment of upper inner arm crepiness/laxity with injectable poly-L-lactic acid (PLLA, Sculptra® Aesthetic)

Approximately 1 year (8 visits)

Compensation: Up to $550


Females 18-60yrs Fitzpatrick Skin Type I-IV

Concern :
Moderate to severe cellulite on the buttocks

Study Specifics:

This trial will test the effects of different methods to try to decrease potential bruising of the buttocks after treatment with QWO.

Approximately 30 weeks (18 visits)

Compensation: Up to $975

Hip Dell

Females 30-60 Years of age

Concern :
Moderate to severe Hip Dell volume deficit

Study Specifics:
To assess efficacy of adipose tissue generation (adipogenesis) and volumization following treatment of the hip dell with injectable poly-L-lactic acid (PLLA, Sculptra® Aesthetic;)

15 Months, (11 Visits)

Compensation: $700

Glabellar Lines

Males/Females 18 Years and older

Concern :
Moderate to severe frown lines between the eyebrows.

Study Specifics:
To evaluate the efficacy  of AGN-151586 over multiple repeat
treatments of the study drug in subjects with moderate to severe Glabellar Lines. 

Up to 5 Months ( 14 Visits)

Compensation: Up to $1,150

Actinic Keratosis

Males/Females 35-85yrs

Concern :
Mild to moderate actinic keratosis on both hands or arms

Study Specifics:

This trial will compare the efficacy of Ameluz activated by Red Light versus Levulan activated by Blue Light for the treatment of Actinic Keratosis on the Upper Extremities

Approximately 1 year (6 visits)

Compensation: Up to $400

Psoriasis Microneedle Patch

Healthy Male / Female Ages 18+

Concern: Observational study to examine RNA biomarkers of psoriasis subjects through the application of a Microneedle patch

Study Specifics: For male or female patients 18+ who have been diagnosed with Psoriasis with the affected area greater than 2 cm in diameter. Patients must be treated with IL-17 (Cosentyx) and IL-23 (Skyrizi/Tremfya/Iilumya) therapy once enrolled.

Duration: 12 weeks

Compensation: up to $350 ($50 per visit)

Laser Hair Removal for Red, Grey, Blonde Hair

Female ages 18-70

Concern:Unwanted hair in armpit area

Study specifics:For women ages 18-70. This trial uses a new treatment for underarm hair reduction in females with naturally light hair such as grey, blonde, or red.

Duration: 4 months (5 visits)

Compensation: $20 per visit

Submental Fat Reduction

Healthy Males/Females 18-65 Years Old

Concern :
Visible fat under the chin.

Study Specifics:
To characterize the safety and efficacy of repeated treatment sessions
of 10XB-101 with that of the vehicle control in adult subjects with localized subcutaneous fat in
the submental area.

12 Months (15 Visits)

Compensation: Up to $850

Basal Cell Carcinoma

Ages 18 and Older, Male/Female

Concern: At least one basal cell located on the body.

Study Specifics: For men and women, age 18+. This trial includes using a topical along with photodynamic therapy in the treatment of superficial basal cell carcinoma.

Duration: 8 months (10 visits)

Compensation:Up to $2600 Status:Enrolling


Male/Female 25-70

Concern: Leg veins

Study Specifics: For men and women, age 25-70. This trial uses Sclerotherapy injections to help treat and improve spider veins in both legs.

Duration: 12 weeks (5 visits)

Compensation: $$ Requires payment from subject – $333

Sun Damage

Observational Study for Healthy Males and Females 21+

Concern: Collecting photodamaged skin samples for observational purposes

Study Specifics: This trial will collect skin samples via Dermtech patch to test genetic changes in the skin from sun damage

Duration: 1 visit

Compensation: $25


For Males/Females 16 years and older for acne and 18 years and older for acne scars

Concern: Moderate facial acne or acne scars for all skin types

Study Specifics: Investigational laser aimed for treatment of acne and comparison of FDA approved lasers for acne scars

Duration: 8-16 Months

Compensation: Yes

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The information available on this website is provided for informational purposes only. This information is not intended to replace a medical consultation where a physician’s judgment may advise you about specific disorders, conditions and/or treatment options. We hope the information will be useful for you to become more educated about your health care decisions.

*Please note: Free in-person consultations are available with Dr. Angra, Leysin Fletcher, PA-C, and medical aesthetician Farzaneh Momeni-Salami, while all consultations with Drs. Goldman, Butterwick, Groff, Fabi, Wu, and Boen are subject to a $250 fee that will be applied towards your treatment. All virtual consultations are also subject to a fee that will be applied towards treatment. Promotions are not available with Dr. Goldman. We do not accept insurance for any of our procedures. Any questions – feel free to call us at 858.943.2113.