Wegovy® and Ozempic® have become household names on social media, especially among those seeking dramatic weight loss. But as more people achieve success with GLP-1 medications, many are noticing an unintended side effect: “Ozempic face” or “Wegovy face.” These terms describe a hollow, gaunt, or sagging appearance that often results from rapid fat loss — especially in the face.
At Cosmetic Laser Dermatology, we understand how discouraging these facial changes can feel — especially when your body is transforming in all the right ways. Our expert dermatologists offer a range of innovative, non-surgical facial rejuvenation and skin tightening treatments to help restore volume, smooth wrinkles, and lift sagging areas, so your reflection reflects your hard work.
What is Wegovy/Ozempic Face?
“Ozempic face” or “Wegovy face” refers to the facial volume loss and sagging skin that can occur when patients rapidly shed weight using semaglutide-based medications like Ozempic® and Wegovy®. Since facial fat pads shrink faster than other areas of the body, the result is often a more angular, sunken, or prematurely aged appearance.
The phrase was coined by dermatologists who began seeing a spike in patients experiencing these side effects. Fortunately, modern dermatologic treatments offer targeted solutions to rebuild structure, stimulate collagen, and restore facial harmony — no surgery required.
What Are Wegovy and Ozempic?
Ozempic is FDA-approved for Type 2 diabetes, and Wegovy is approved for chronic weight management in patients with obesity. Both contain semaglutide, a GLP-1 receptor agonist that curbs appetite and helps regulate blood sugar levels. These medications are injected weekly and have become popular for their effectiveness in producing rapid weight loss.
While the benefits are real, facial fat loss is one of the lesser-discussed side effects — and it’s where our cosmetic dermatology team can help.
How We Treat Wegovy Face: Proven Dermatologic Solutions
Several treatment options can help improve loose, sagging skin after weight loss, but choosing the right procedures depends on your unique needs and aesthetic goals.
Dermal Fillers
One of the fastest and most effective ways to restore lost volume is through hyaluronic acid fillers like Juvéderm® and Restylane®. These injectables can:
- Plump sunken cheeks and temples
- Soften deep nasolabial folds
- Rebuild contour in the mid-face and jawline
For deeper volume loss, Juvéderm® Voluma and Restylane® Lyft can create structure and lift. We also use softer fillers like Vollure or Refyne to smooth and rehydrate thinner areas while maintaining a natural look.
Dermal Fillers
Injectables like dermal fillers are one of the most effective treatments for restoring facial volume after weight loss. We offer a wide range of hyaluronic acid (HA) fillers, including Juvéderm® and Restylane®, to treat volume loss.
These injectables can:
- Rebuild contour in the mid-face and jawline
- Plump sunken cheeks and temples
- Soften deep nasolabial folds
They are available in a range of formulas, each designed to address specific areas of the face and different degrees of volume loss.
For example, Juvéderm® Voluma is specifically designed to restore volume to the cheeks, which can appear sunken after weight loss. This filler is formulated with a thicker consistency to add structure and lift to the cheeks to restore their natural contours. Similarly, Restylane® Lyft is FDA-approved for cheek augmentation and correction of mid-face contours.
Dermal fillers like Juvéderm® Vollure are softer gels that add volume to the nasolabial folds, which become more apparent after weight loss. The filler restores volume and enhances facial contours to restore a healthier, more youthful appearance.
Biostimulators
Biostimulators like Radiesse® and Sculptra® consist of gel microspheres that add volume and stimulate fibroblastic function to increase collagen, elastic fiber, and hyaluronic acid production. Similar to HA fillers, collagen stimulators are used for pinpoint injections to restore volume and definition. However, while HA fillers last up to six months or longer, collagen stimulators can last up to two years.
We use Radiesse and Sculptra to help add volume to the face over time. These injectables offer an effective treatment option for patients who have drastically lost weight, as they can gradually restore and enhance facial contours for more natural and long-lasting results.
If you’re looking for long-term correction, biostimulatory injectables like Sculptra® and Radiesse® are ideal for rebuilding collagen and restoring gradual volume. These treatments are especially effective for:
- Thin skin texture
- Widespread fat loss
- Jawline and lower face definition
They also pair beautifully with skin tightening procedures for total facial rejuvenation.
Laser & Light Treatments
Cosmetic Laser Dermatology offers the latest technology, including 60+ laser and light devices, to treat concerns such as wrinkles and sagging skin. To improve skin tone and lift sagging areas, we often combine injectables with non-invasive energy treatments that stimulate collagen and elastin production.
RF microneedling involves using a device that combines microneedling with radiofrequency energy to penetrate the skin and stimulate fibroblastic function to increase collagen, elastic fiber, and hyaluronic acid production. This treatment can be used to address the loss of skin elasticity and sagging skin associated with Ozempic or Wegovy use.
Lasers like the Lumenis UltraPulse® Encore CO2 laser and the Sciton Erbium:YAG laser offer fractional resurfacing and are excellent at treating deeper wrinkles and severe textural issues from weight loss. By creating microscopic thermal channels in the skin, fractional lasers trigger new collagen and elastin fiber production. The result is tighter skin with reduced wrinkles.
Ultherapy®, Thermage FLX®, and Sofwave™ are another option for treating sagging skin. These use ultrasound or radiofrequency technology to stimulate fibroblastic function to increase collagen, elastic fiber, and hyaluronic acid production to tighten and firm the skin over time. It can lift the eyebrow, chin, and neck area and improve lines and wrinkles in the low neckline.
Thermage FLX
Thermage FLX uses radio frequency energy to tighten skin and smooth facial contours. It’s a go-to treatment for post-weight loss skin laxity, especially for:
- Lower cheeks
- Jawline
- Neck and under-chin
Thermage FLX is safe for all skin types and tones and can even be combined with Fraxel® laser resurfacing for complete skin rejuvenation using our new ThermaFrax procedure.
Finally, since Wegovy and Ozempic use can also produce muscle atrophy, we use the CoolTone muscle stimulator and Lumenis Trivantage to build up lost muscle.
Ultherapy & Sofwave™
These ultrasound-based devices target deeper layers of the skin to lift and firm areas like the brow, jawline, and décolleté. They’re often used on patients with visible drooping after significant weight loss and can be combined with CoolLipo for more sculpted definition.
CoolLipo: Precision Fat Reduction
In cases where facial contours are uneven or submental fullness lingers, CoolLipo offers laser-assisted fat sculpting with skin-tightening benefits. It’s ideal for:
- Refining the neck or jawline
- Enhancing definition after weight loss
- Patients who want permanent results with minimal downtime
Unlike traditional liposuction, CoolLipo also tightens the skin from beneath, making it a powerful solution for post-Ozempic patients with mild laxity and stubborn fat pockets.
Comprehensive Skin Tightening Treatments
Whether your concern is loss of elasticity, sagging cheeks, or fine lines that suddenly feel more pronounced, we tailor each plan using the most advanced technology available.
In addition to fillers and lasers, we offer:
- RF microneedling (Morpheus8, Secret RF)
- Fractional lasers (CO2, Erbium:YAG)
- Muscle stimulation (CoolTone, TriVantage) for post-weight loss atrophy
Our team can guide you through a plan that fits your timeline, goals, and skin type — without overcorrecting or creating an artificial look.
Get Effective Treatment for Wegovy/Ozempic Face in San Diego
You worked hard to lose the weight — now let us help you look as vibrant as you feel. With over 60 devices and 7 board-certified dermatologists, Cosmetic Laser Dermatology offers the most comprehensive cosmetic treatment menu in San Diego under one roof.
Whether you need volume, lifting, contouring, or all of the above, our experts are committed to providing the best aesthetic and anti-aging procedures that restore balance without surgery or downtime.
With the most advanced skin treatments in San Diego and industry-leading research, patients can achieve the best possible outcome.
If you are ready to treat Ozempic or Wegovy face or other loose skin issues, Cosmetic Laser Dermatology is here to help.
Schedule a consultation today and rediscover your confidence, your way.
