La Jolla Dermal Filler Cosmetic TreatmentsThe Restylane line of fillers, which includes Restylane Silk and Restylane Lyft, is already one of the most popular non-invasive wrinkle treatments on the market due to its versatility and effectiveness. When the skin treatment manufacturer Galderma announced that its two new Restylane hyaluronic acid wrinkle reduction fillers had received FDA approval in December 2016, the announcement was met with a lot of excitement by the dermatologic community and patients alike.

The two new injectable treatments, called Restylane Refyne and Restylane Defyne, both address moderate to severe, deep facial wrinkles and can help rejuvenate your appearance. At Cosmetic Laser Dermatology in San Diego, our board-certified dermatologists are among a select group of U.S. doctors chosen to provide the new treatments and have the experience, insight, and skill to determine the best facial wrinkle treatment for you.

If you’re looking for an effective filler treatment for your laugh lines in San Diego, these two new Restylane dermal fillers by Galderma could be just what you need.

The Restylane Line of Facial Filler Injections

Restylane facial fillers are all made with a biodegradable gel that contains no animal-based ingredients, which virtually erases any chances of an allergic reaction. The entire line of dermal fillers is manufactured with hyaluronic acid (HA), a naturally hydrating substance that is also found in the human body, making it biocompatible and safe to use as an injectable filler.

Hyaluronic acid synthesizes easily with your skin, binding to your skin’s stores of moisture for optimal hydration retention. The HA injectable plumps your skin by filling in empty spaces between the elastin and collagen fibers deep within your skin. With proper levels of hyaluronic acid, your skin is smoother, tighter, and more supple.

HA dermal fillers, such as Restylane Lyft and Restylane Silk, are more compatible with your body than other non-surgical facial wrinkle treatments because your body absorbs them more readily and safely. Your skin looks and feels smoother and fresher, taking years off your appearance.

What Makes Restylane Refyne and Restylane Defyne Unique?

The two new Restylane treatments are considered “next-generation” HA dermal fillers because they are manufactured using an innovative new technology called XpresHAn, which gives these gels more flexibility and support than other HA fillers.

With the flexibility that Restylane Refyne and Restylane Defyne deliver, the filler gel moves easily with your skin, allowing your facial movements to look and feel natural.

La Jolla Hyaluronic Acid Facial Filler Technology

Is There a Difference Between These Facial Fillers?

Both Restylane Refyne and Restylane Defyne are FDA-approved to specifically address laugh lines, or nasolabial folds, the lines that develop from the corners of the mouth to the nostrils. Furthermore, they both deliver natural-looking results that have been found in clinical trials to last as long as 12 months.

San Diego Cosmetic Dermatology Dermal Filler

But there is a small difference between these revolutionary fillers.

Restylane Refyne is for the treatment of moderate to severe facial folds, creases, lines, and wrinkles. It is designed to correct nasolabial folds and is the more flexible of the two treatments, hence offering softer, more subtle improvements.

Restylane Defyne also treats moderate to severe, deep facial folds and wrinkles, but it is specifically designed to go deeper. The gel is slightly less flexible, which means that it provides extra support for deeper folds and wrinkles.

Ideal Dermal Fillers for First-Time Patients

One of the reasons that Restylane Refyne and Restylane Defyne are highly anticipated by both doctors and patients alike is that they were designed, in part, for patients who had previously been hesitant to try dermal fillers. Not only do the two new products offer more versatility to the entire line of facial fillers, but the innovative technology with which they are made provides subtle, flexible results that make both HA fillers ideal if you’ve been hesitant in the past.

Learn more about hyaluronic acid at

Additionally, there is virtually no downtime necessary for these facial fillers. The potential side effects are typically mild and don’t last more than a few days. Some of the possible side effects of Restylane Refyne or Restylane Defyne that could occur, usually around the facial wrinkle treatment site, include the following:

  • Soreness
  • Inflammation
  • Tenderness
  • Swelling
  • Bruising
  • Itching

Which is Better for You?

This question can only be answered during an appointment at our San Diego practice. During this consultation, our dermatologists can determine whether Restylane Refyne or Restylane Defyne is the better facial wrinkle treatment for you based on the depth of the lines and wrinkles that you want to treat, among other factors. In fact, in some instances, a combination of the two fillers could be the most effective plan as both facial fillers can be administered in the same treatment session.

Receive Expert Laugh Lines Treatment in San Diego

These two new dermal fillers are highly effective, so if you have laugh lines that you’d like to reduce, Restylane Refyne or Restylane Defyne might be the ideal treatment for you. To find out more, don’t hesitate to schedule a consultation at Cosmetic Laser Dermatology, which is located in the San Diego UTC area, just minutes from Del Mar, La Jolla, and Downtown. Contact us online or by calling (858) 943-2113.

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