RHA Dermal Fillers

A Center of Excellence in the Art and Science of Rejuvenation, Cosmetic Laser Dermatology has now added RHA Dermal Fillers to its lineup of anti-aging treatments. Our board-certified dermatologists in San Diego, CA are highly respected in the field for their use of revolutionary treatments, continued participation in clinical trials, as well as their constant involvement in advanced medical research, including the studies for the RHA collection of dermal fillers. By combining these cosmetic breakthroughs in science and medicine, we can bring you the ultimate care in skin rejuvenation. 

How Do RHA Dermal Fillers Work?

Your face is dynamic. It makes countless movements and micro-movements daily. Squinting, smiling, frowning, talking, and laughing can create wrinkles and folds in the areas of the face that move repetitively. These dynamic wrinkles and folds should be treated without creating a stiff and unnatural appearance when making these facial movements after a treatment.

RHA dermal fillers are advanced injectables that can address these concerns because they are uniquely designed to seamlessly adapt to the dynamic demands of your face, helping to achieve a more natural look at rest and in motion. These fillers are injected into the mid-to-deep dermis or deep dermis to superficial subcutaneous tissue to smooth facial wrinkles and folds. The resilience of these fillers comes from their gentle manufacturing process. By preserving the natural structure of hyaluronic acid (HA), which helps provide moisture, volume, and structure to the skin, these fillers can closely mimic the natural HA found in your skin, allowing the formula to stretch more easily to the dynamic areas of the face, resulting in a more natural look. To learn more about RHA fillers, visit fda.gov

Benefits of RHA Fillers

• Correct dynamic facial wrinkles and folds while remaining undetectable.
• They can address aesthetic concerns like:
  • dynamic wrinkles
  • nasolabial folds
  • expression lines around the mouth
  • marionette lines
  • chin lines
• Restore volume and contour facial areas such as the cheeks, chin, jawline, and lips as they sculpt and balance facial proportions.
• RHA Fillers adapt to the dynamic areas of the face, allowing for natural movement. Because these fillers are very similar to your skin’s HA, they adapt so well to your skin tissues that they can provide structural support while softening the look of the skin as it moves expressively, maintaining the vitality of your face. RHA may allow for the greatest flexibility in your most dynamic facial areas. 
• Because RHA products move with your face, they take longer to break down, producing results that may last longer than traditional fillers.

Clinical Studies

The safety and efficacy of Revance Therapeutics’s RHA fillers have been demonstrated through clinical studies, including an 18-month head-to-head, randomized, and controlled European clinical study of RHA 2, 3, and 4 for the treatment of nasolabial folds, which was published in Dermatologic Surgery.

Results showed: 

• Overall physician preference for RHA Collection products due to ease of injection and product placement, immediate results, and results after massaging of the injected tissue
• High levels of improved satisfaction immediately after injection and in the long-term for both investigators and participating subjects 
• Fewer touch-ups were needed by (or at) day 14 with gels in the RHA Collection (26.7% vs 35.6% with comparators) 
• Better long-term improvement of nasolabial folds volume with gels in the RHA Collection based on 3D skin topography measurements. 

A 15‐month, prospective, multicenter, controlled, randomized, double‐blind, within‐subject (split‐face) clinical trial was also conducted on 140 subjects with moderate‐to‐severe nasolabial folds. Results showed the noninferiority of the resilient HA filler to its comparator, aesthetic improvement, durably high subject satisfaction, and an overall trend toward higher scores for the resilient HA filler. To learn more about the clinical trial, visit ncbi.nlm.nih.gov

Fillers vs. Neuromodulators

RHA fillers are designed to correct mid-to-deep dermis imperfections, particularly dynamic lines around the eyes, nose, and mouth that can typically only be treated with neuromodulators such as Botox. However, the RHA line of products are not neuromodulators but are dermal fillers. RHA dermal fillers are composed of HA, which is already found in your skin, while neuromodulators such as Botox and Dysport are made from an active ingredient known as botulinum toxin. Not only can RHA fillers smooth lines and wrinkles, but they may also restore volume, which neuromodulators cannot achieve.

What sets RHA dermal fillers apart from other injectables is their ability to treat dynamic wrinkles and folds and allow for facial movement. RHA dermal fillers may integrate well into the tissue, making them less detectable, while providing softer, natural-looking results that may look equally good at rest and in motion.